CETRIMONIUM BROMIDE

PRODUCT IDENTIFICATION
CAS NO.

57-09-0

CETRIMIDE
EINECS NO. 200-311-3
FORMULA CH3(CH2)15N(Br)(CH3)3
MOL WT. 364.45

H.S. CODE

2923.90

TOXICITY

 Oral rat LD50: 410 mg/Kg
SYNONYMS Cetrimonium bromide; HTAB; CTAB; CTABr;
Hexadecyltrimethylammonium bromide; Cetab; Cetyltrimethylammonium Bromide; N-Hexadecyltrimethylammonium Bromide; Trimethylcetylammonium bromide; Ammonium, hexadecyltrimethyl-, bromide; Palmityltrimethyl ammonium bromide; N,N,N-trimethyl-1-Hexadecanaminium bromide;
RAW MATERIALS

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE

white crystalline powder
MELTING POINT

235 C (Decomposes)
BOILING POINT

 
SPECIFIC GRAVITY

>1.0
SOLUBILITY IN WATER Slightly soluble
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 Health: 2 Flammability: 1 Reactivity: 0

REFRACTIVE INDEX

 
FLASH POINT

 
STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS
Quaternary ammonium compounds are any of a group of ammonium salts in which organic radicals have been substituted for all four hydrogens of the original ammonium cation. They has a central nitrogen atom which is joined to four organic radicals and one acid radical. The organic radicals  may be alkyl, aryl, or aralkyl, and the nitrogen can be part of a ring system. They are prepared by treatment of an amine with an alkylating agent. They show a variety of physical, chemical, and biological properties and most compounds are soluble in water and strong electrolytes. Such compounds include
  • Benzalkonium Chloride (CAS RN: 8001-54-5)
  • Benzethonium Chloride (CAS RN: 121-54-0)
  • Cetalkonium Chloride(CAS RN: 122-18-9)
  • Laurtrimonium Bromide (CAS RN: 1119-94-4)
  • Myristyltrimethylammonium bromide (CAS RN: 1119-97-7)
  • Cetrimide (CAS RN: 8044-71-1)
  • Cetrimonium Bromide ( CAS RN: 57-09-0)
  • Cetylpyridinium Chloride (CAS RN: 123-03-5)
  • Stearalkonium Chloride ( CAS RN: 122-19-0)

They have properties of disrupting micro-organisms' cell processes and surfactants. These compounds are used as

  • Active Ingredient for Conditioners
  • Antistatic Agent
  • Detergent Sanitisers
  • Softner for textiles and paper products
  • Phase Transfer Catalyst
  • Antimicrobials
  • Disnfection Agents And Sanitizers
  • Slimicidal Agents
  • Algaecide
  • Emulsifying Agents
  • Pigment Dispersants
SALES SPECIFICATION (BP)

98% SOLID

APPEARANCE

white crystalline powder

CONTENT

98.0% min

WATER

0.5% max

FREE AMINE

0.7% max

40% SOLUTION

APPEARANCE

 Clear to pale yellowish viscous liquid

ACTIVE CONTENT

39.0% min
Free amine

0.7% max
Ethanol 7.0 - 8.0%
Water 52.0 - 53.0%

COLOR (Lovibond)

 Y 10 max R 1.5 max
TRANSPORTATION
PACKING
200kgs in Drum
HAZARD CLASS Not regulated
UN NO. 1759
OTHER INFORMATION
European Hazard Symbols: XN, Risk Phrases: 22-36/37/38, Safety Phrases: 26-37
GENERAL DESCRIPTION OF ANTISEPTIC AGENT
Antiseptic agent is a substance which kills or inhibits the growth of disease-causing bacteria and other microorganisms. It is essentially nontoxic to to be applied to the skin or mucous membranes. (Disinfectant including cresol, bleaching powder, and phenol is in general toxic to cells of the body). Common antiseptic agents are Benzalkonium Chloride, Cetrimide, Chlorhexidine, Hexachlorophene, Iodine Compounds, Mercury Compounds (Thimerosol), Alcohol and Hydrogen Peroxide, Hexamine Hippurate, Triclosan, Cetylpyridinium Chloride, And Dequalinium. Other substances which can be used for antiseptic purpose include Boric acid and volatile oils such as Methyl Salicylate.

Hexachlorophene and Benzalkonium Chloride are used primarily in hand or face washes. Benzalkonium Chloride must not be applied to areas which have not been fully rinsed as it is inactivated by organic compounds. Benzalkonium application many include disinfecting instruments and preservativing drugs in low concentration form.

Iodine compounds have the widest spectrum of antiinfectives against bacteria, fungi, spores, protozoa, viruses, and yeasts. Aqueous iodine are less effective than alcoholic solutions, but alcoholic component is drying and irritating to abraided skin. Povidone iodine is convenient to use as it is less irritating, but not as effective.

Chlorhexidine is used as a safe antiseptic or disinfectant to apply to prevent body infection and in oral rinses for treating sore gums and mouth ulcers and preventing plaque on teeth. It is used in the form of acetate, gluconate or hydrochloride, either alone or in combination with others such as cetrimide.

Cetrimide is an antiseptic agent with detergent properties. It has the wide spectrum of antiinfectives against bacteria and fungi. It is used as an ingredient of shampoos for treating seborrhoea and psoriasis. A very dilute solution can be applied topically for the relief of sore gums.

Hippuric Acid, an amino acid glycine, is excreted from the body and is used in urinary system drugs. Hexamine hippurates is helpful for preventing and treating infections of the urinary system; it acts by being transformed to formaldehyde.

Triclosan is a very popular antibacterial agent. It is used in hospitals for cleansing and disinfecting the skin of patients and surgeons. It is used in cosmetics, household goods and personal care products. It is also used in plastics and textiles for antibacterial activity purpose.

Cetylpyridinium chloride is used in oral rinses for cleaning mouth and treating minor throat or mouth infections and teething problems.

Dequalinium chloride is antiinfectives against bacteria and fungi. It is used in treating bacterial or fungal infections of mouth and throat.